Mount Sinai Health System in New York City has partnered with OpenEvidence to integrate the clinical decision support platform directly into its Epic EHR, marking the AI company’s first enterprise health system agreement.
Key Details:
- The platform will be accessible to all clinicians across Mount Sinai’s seven-hospital network, including physicians, nurses, and pharmacists.
- Users can ask medical questions in natural language and receive answers backed by clinical guidelines and peer-reviewed literature.
- Girish Nadkarni, MD, Chief AI Officer at Mount Sinai, emphasized that the integration provides real-time, evidence-based insights within clinicians’ workflows, supporting more informed decision-making.
- OpenEvidence, currently valued at $12 billion, is reported as the most commonly used medical AI platform among U.S. physicians.
This collaboration highlights Mount Sinai’s focus on AI that is clinically meaningful, trusted, and seamlessly integrated into care delivery.
Source: Becker’s Hospital Review, Giles Bruce, Mount Sinai inks 1st enterprise deal with OpenEvidence (2026).


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